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Detailed Immune Marker Typing, Class I And II

Nationwide rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

Facilitymedian $617 · 10th–90th $302$1,7380%10%10th90th$617Professionalmedian $309 · 10th–90th $191$7410%20%10th90th$309$0.5$5.0$50.0$500.0$5.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$645.65
Typical High
$1,819.70
Aetna
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$295.12
Typical High
$707.95
BCBS
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$512.86
Typical High
$1,584.89
BCBS
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$295.12
Typical High
$851.14
Cigna
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$741.31
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$416.87
Typical High
$831.76
United
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$346.74
Typical High
$467.74
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$208.93
Typical High
$549.54