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Detailed Immune Marker Typing, Class I And II

Colorado rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$457

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $457 for this service. The price depends on where it is billed: about $263 from a physician practice, and about $955 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$263$219 to $309
FacilityA hospital or hospital-owned outpatient department$955$479 to $1,514

How much rates vary

Facilitymedian $955 · 10th to 90th $263 to $1,585Professionalmedian $263 · 10th to 90th $145 to $407
$100.0$500.0$2.0K$10.0Kfacility $955professional $263

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$1,202.26
Typical High
$1,584.89
Aetna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$263.03
Typical High
$371.54
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$436.52
Median
$1,023.29
Typical High
$1,737.80
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$144.54
Typical High
$446.68
Cigna
Setting
Facility
Modifier
Global
Typical Low
$204.17
Median
$223.87
Typical High
$912.01
Cigna
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$199.53
Typical High
$501.19
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$346.74
Typical High
$588.84
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$489.78
Typical High
$3,019.95
Select Health
Setting
Facility
Modifier
Global
Typical Low
$363.08
Median
$645.65
Typical High
$724.44
Select Health
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$346.74
Typical High
$512.86
United
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$512.86
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$199.53
Typical High
$239.88

Where Colorado sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Colorado $457 · 11th of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.