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Detailed Immune Marker Typing, Class I And II

Michigan rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$331

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $331 for this service. The price depends on where it is billed: about $295 from a physician practice, and about $331 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$295$257 to $331
FacilityA hospital or hospital-owned outpatient department$331$331 to $575

How much rates vary

Facilitymedian $331 · 10th to 90th $331 to $603Professionalmedian $295 · 10th to 90th $257 to $447
$10.0$50.0$200.0$1.0Kfacility $331professional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$602.56
Aetna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$331.13
Typical High
$407.38
BCBS
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$389.05
Typical High
$691.83
BCBS
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$257.04
Typical High
$257.04
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$346.74
Typical High
$478.63
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$407.38
Typical High
$1,096.48
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$446.68
Typical High
$588.84
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$398.11
Typical High
$776.25
United
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$346.74
Typical High
$416.87
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$281.84
Typical High
$467.74

Where Michigan sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Michigan $331 · 38th of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.