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Detailed Immune Marker Typing, Class I And II

Michigan rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$331

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $331 for this service. The price depends on where it is billed: about $331 from a physician practice, and about $331 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$331$257 to $447
FacilityA hospital or hospital-owned outpatient department$331$331 to $457

How much rates vary

Facilitymedian $331 · 10th to 90th $257 to $646Professionalmedian $331 · 10th to 90th $245 to $575
$10$20$50$100$200$500$1Kfacility $331professional $331

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$512.86
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$165.96
Median
$165.96
Typical High
$257.04
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$66.07
Median
$66.07
Typical High
$102.33
Aetna
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$338.84
Typical High
$407.38
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$158.49
Median
$169.82
Typical High
$173.78
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$63.10
Median
$67.61
Typical High
$69.18
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$371.54
Typical High
$645.65
BCBS Michigan
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$257.04
Typical High
$257.04
Cigna
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$281.84
Typical High
$467.74
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$1,202.26
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$165.96
Median
$165.96
Typical High
$257.04
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$66.07
Median
$66.07
Typical High
$102.33
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$446.68
Typical High
$588.84
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$165.96
Median
$165.96
Typical High
$165.96
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
Priority Health
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$346.74
Typical High
$489.78
United
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$309.03
Typical High
$416.87
United
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$281.84
Typical High
$446.68

Where Michigan sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 36th of 51

$331

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.