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Detailed Immune Marker Typing, Class I And II

North Carolina rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$407

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $407 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $575 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$275 to $427
FacilityA hospital or hospital-owned outpatient department$575$437 to $1,096

How much rates vary

Facilitymedian $575 · 10th to 90th $295 to $1,514Professionalmedian $309 · 10th to 90th $191 to $490
$10.0$50.0$200.0$1.0Kfacility $575professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$912.01
Typical High
$1,513.56
Aetna
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$275.42
Typical High
$457.09
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$489.78
Typical High
$489.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$1,445.44
Typical High
$1,445.44
BCBS
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$426.58
Typical High
$549.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$758.58
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$218.78
Typical High
$467.74
Medcost
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$346.74
Typical High
$602.56
Medcost
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$275.42
United
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$457.09
Typical High
$575.44
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$234.42
Typical High
$467.74
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$1,659.59
Median
$1,659.59
Typical High
$1,659.59
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$2,570.40

Where North Carolina sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $407 · 21st of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.