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Detailed Immune Marker Typing, Class I And II

Alabama rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$174

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $257 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$257$200 to $398
FacilityA hospital or hospital-owned outpatient department$174$174 to $174

How much rates vary

Facilitymedian $174 · 10th to 90th $174 to $295Professionalmedian $257 · 10th to 90th $145 to $398
$200$500$1Kfacility $174professional $257

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$398.11
Median
$398.11
Typical High
$537.03
Aetna
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$398.11
Typical High
$398.11
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$141.25
Median
$199.53
Typical High
$199.53
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$56.23
Median
$79.43
Typical High
$79.43
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$239.88
Median
$354.81
Typical High
$354.81
Cigna
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$295.12
Typical High
$1,096.48
Cigna
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$208.93
Typical High
$1,949.84
United
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$309.03
Typical High
$346.74
United
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$208.93
Typical High
$281.84

Where Alabama sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$174

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.