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Detailed Immune Marker Typing, Class I And II

Illinois rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$295

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $295 for this service. The price depends on where it is billed: about $282 from a physician practice, and about $537 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$282$240 to $347
FacilityA hospital or hospital-owned outpatient department$537$355 to $708

How much rates vary

Facilitymedian $537 · 10th to 90th $295 to $955Professionalmedian $282 · 10th to 90th $3 to $692
$10.0$100.0$1.0Kfacility $537professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$537.03
Typical High
$794.33
Aetna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$295.12
Typical High
$707.95
BCBS
Setting
Facility
Modifier
Global
Typical Low
$436.52
Median
$1,412.54
Typical High
$4,365.16
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$239.88
Typical High
$269.15
Cigna
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$794.33
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$478.63
Typical High
$630.96
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$602.56
Typical High
$3,019.95
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$446.68
United
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$691.83
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$257.04
Typical High
$467.74

Where Illinois sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $295 · 45th of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.