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Detailed Immune Marker Typing, Class I And II

Maryland rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$282

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $282 for this service. Most negotiated rates run $257 to $309.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $145 · 10th to 90th $145 to $263Professionalmedian $282 · 10th to 90th $195 to $447
$5.0$20.0$100.0$500.0$2.0Kfacility $145professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$281.84
Typical High
$467.74
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$309.03
Typical High
$346.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$257.04
Typical High
$602.56
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$416.87
Typical High
$512.86
United
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$144.54
Typical High
$263.03
United
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$199.53
Typical High
$316.23
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$338.84
Typical High
$338.84

Where Maryland sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Maryland $282 · 48th of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.