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Detailed Immune Marker Typing, Class I And II

Nebraska rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$282

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $282 for this service. The price depends on where it is billed: about $229 from a physician practice, and about $490 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$229$209 to $692
FacilityA hospital or hospital-owned outpatient department$490$355 to $851

How much rates vary

Facilitymedian $490 · 10th to 90th $209 to $1,349Professionalmedian $229 · 10th to 90th $195 to $1,738
$200$500$1Kfacility $490professional $229

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$812.83
Typical High
$1,698.24
Aetna
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$812.83
BCBS Nebraska
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$489.78
Typical High
$954.99
Cigna
Setting
Professional
Modifier
None
Typical Low
$660.69
Median
$676.08
Typical High
$831.76
Medica
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$707.95
Typical High
$1,905.46
Medica
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$1,737.80
Midlands
Setting
Professional
Modifier
None
Typical Low
$630.96
Median
$630.96
Typical High
$630.96
Midlands
Setting
Professional
Modifier
None
Typical Low
$630.96
Median
$630.96
Typical High
$630.96
United
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$144.54
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$208.93
Typical High
$1,412.54

Where Nebraska sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 44th of 51

$282

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.