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Detailed Immune Marker Typing, Class I And II

Maine rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$282

Typical negotiated rate. In Maine, October 2026.

Insurers have agreed to pay about $282 for this service. Most negotiated rates run $209 to $427.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $457 · 10th to 90th $331 to $3,890Professionalmedian $209 · 10th to 90th $138 to $468
$200$500$1K$2K$5Kfacility $457professional $209

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$263.03
Median
$281.84
Typical High
$380.19
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$457.09
Typical High
$3,890.45
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$173.78
Typical High
$223.87
Cigna
Setting
Facility
Modifier
None
Typical Low
$549.54
Median
$549.54
Typical High
$776.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$346.74
Typical High
$346.74
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$346.74
Typical High
$831.76
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$281.84
Median
$281.84
Typical High
$380.19
United
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$281.84
Typical High
$831.76

Where Maine sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 43rd of 51

$282

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.