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Detailed Immune Marker Typing, Class I And II

Maine rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$347

Typical negotiated rate. In Maine, July 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $347 from a physician practice, and about $562 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$347$282 to $347
FacilityA hospital or hospital-owned outpatient department$562$347 to $1,549

How much rates vary

Facilitymedian $562 · 10th to 90th $347 to $4,365Professionalmedian $347 · 10th to 90th $209 to $417
$200$500$1K$2K$5Kfacility $562professional $347

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$281.84
Typical High
$346.74
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$4,365.16
Typical High
$4,677.35
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$208.93
Typical High
$446.68
Cigna
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$776.25
Typical High
$776.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$346.74
Typical High
$346.74
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$416.87
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$1,548.82
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$346.74
Typical High
$380.19
United
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$346.74
Typical High
$676.08

Where Maine sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 37th of 51

$347

AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.