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Detailed Immune Marker Typing, Class I And II

Ohio rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$347

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $275 from a physician practice, and about $513 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$275$219 to $347
FacilityA hospital or hospital-owned outpatient department$513$347 to $724

How much rates vary

Facilitymedian $513 · 10th to 90th $324 to $776Professionalmedian $275 · 10th to 90th $170 to $724
$200$500$1Kfacility $513professional $275

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$660.69
Typical High
$776.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$281.84
Typical High
$776.25
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$316.23
Median
$363.08
Typical High
$630.96
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$213.80
Typical High
$501.19
CareSource
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$398.11
CareSource
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$457.09
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$302.00
Typical High
$851.14
Medical Mutual of Ohio
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$457.09
Typical High
$1,412.54
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$263.03
Typical High
$812.83
Molina
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$309.03
Typical High
$371.54
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$380.19
Typical High
$794.33
United
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$346.74
Typical High
$512.86
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$208.93
Typical High
$478.63

Where Ohio sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 30th of 51

$347

AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.