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Detailed Immune Marker Typing, Class I And II

Kentucky rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$437

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $437 for this service. The price depends on where it is billed: about $468 from a physician practice, and about $347 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$468$282 to $646
FacilityA hospital or hospital-owned outpatient department$347$288 to $513

How much rates vary

Facilitymedian $347 · 10th to 90th $269 to $933Professionalmedian $468 · 10th to 90th $209 to $1,660
$100$200$500$1Kfacility $347professional $468

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$288.40
Typical High
$512.86
Aetna
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$281.84
Typical High
$446.68
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$346.74
Typical High
$363.08
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$645.65
Typical High
$645.65
CareSource
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$416.87
Typical High
$478.63
CareSource
Setting
Professional
Modifier
None
Typical Low
$371.54
Median
$446.68
Typical High
$575.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$933.25
Typical High
$933.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$1,659.59
Typical High
$1,659.59
United
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$281.84
Typical High
$575.44
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$128.82
Median
$141.25
Typical High
$257.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$51.29
Median
$56.23
Typical High
$104.71

Where Kentucky sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 10th of 51

$437

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.