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TP53 Gene Test For A Known Family Change

Nationwide rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

Facilitymedian $447 · 10th–90th $245$1,3180%10%20%10th90th$447Professionalmedian $263 · 10th–90th $141$5890%20%10th90th$263$0.5$5.0$50.0$500.0$5.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$478.63
Typical High
$1,318.26
Aetna
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$251.19
Typical High
$562.34
BCBS
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$457.09
Typical High
$1,412.54
BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$154.88
Typical High
$501.19
Cigna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$630.96
Typical High
$1,412.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$354.81
Typical High
$741.31
United
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$186.21
Typical High
$457.09