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TP53 Gene Test For A Known Family Change

Ohio rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$263

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $263 for this service. The price depends on where it is billed: about $245 from a physician practice, and about $427 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$245$158 to $295
FacilityA hospital or hospital-owned outpatient department$427$309 to $676

How much rates vary

Facilitymedian $427 · 10th to 90th $251 to $692Professionalmedian $245 · 10th to 90th $123 to $525
$200$500$1Kfacility $427professional $245

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$524.81
Typical High
$741.31
Aetna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$251.19
Typical High
$691.83
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$323.59
Typical High
$562.34
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$158.49
Typical High
$398.11
CareSource
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
CareSource
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$416.87
Typical High
$416.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$398.11
Typical High
$1,548.82
Cigna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$173.78
Typical High
$616.60
Medical Mutual of Ohio
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$407.38
Typical High
$1,698.24
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$173.78
Typical High
$588.84
Molina
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$257.04
Typical High
$323.59
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$371.54
Typical High
$707.95
United
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$457.09
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$186.21
Typical High
$426.58

Where Ohio sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 36th of 51

$263

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.