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TP53 Gene Test For A Known Family Change

Ohio rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$245

Typical negotiated rate. In Ohio, October 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $158 from a physician practice, and about $389 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$158$123 to $269
FacilityA hospital or hospital-owned outpatient department$389$316 to $525

How much rates vary

Facilitymedian $389 · 10th to 90th $282 to $692Professionalmedian $158 · 10th to 90th $123 to $468
$100$200$500$1Kfacility $389professional $158

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$549.54
Typical High
$776.25
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$144.54
Median
$275.42
Typical High
$389.05
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$57.54
Median
$109.65
Typical High
$154.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$245.47
Typical High
$691.83
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$123.03
Median
$123.03
Typical High
$346.74
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$48.98
Median
$48.98
Typical High
$138.04
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$354.81
Typical High
$562.34
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$407.38
CareSource
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$416.87
Cigna
Setting
Facility
Modifier
None
Typical Low
$302.00
Median
$371.54
Typical High
$1,258.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$144.54
Typical High
$446.68
Medical Mutual of Ohio
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$371.54
Typical High
$1,698.24
Medical Mutual of Ohio
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$144.54
Typical High
$416.87
Molina
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$257.04
Typical High
$331.13
SummaCare
Setting
Professional
Modifier
None
Typical Low
$263.03
Median
$380.19
Typical High
$489.78
United
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$275.42
Typical High
$457.09
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$186.21
Typical High
$436.52

Where Ohio sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 39th of 51

$245

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.