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TP53 Gene Test For A Known Family Change

Virginia rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$263

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $263 for this service. The price depends on where it is billed: about $229 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$229$138 to $263
FacilityA hospital or hospital-owned outpatient department$324$309 to $646

How much rates vary

Facilitymedian $324 · 10th to 90th $263 to $1,122Professionalmedian $229 · 10th to 90th $123 to $501
$200$500$1K$2K$5K$10Kfacility $324professional $229

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$588.84
Typical High
$758.58
Aetna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$263.03
Typical High
$588.84
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$1,230.27
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$208.93
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$263.03
Typical High
$302.00
Cigna
Setting
Facility
Modifier
Global
Typical Low
$316.23
Median
$602.56
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$190.55
Typical High
$489.78
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$338.84
Typical High
$426.58
Medcost
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$309.03
Typical High
$524.81
Medcost
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$645.65
Sentara
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$363.08
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$371.54
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$158.49
Typical High
$354.81

Where Virginia sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 37th of 51

$263

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.