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TP53 Gene Test For A Known Family Change

South Carolina rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$245

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $240 from a physician practice, and about $759 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$240$240 to $251
FacilityA hospital or hospital-owned outpatient department$759$245 to $977

How much rates vary

Facilitymedian $759 · 10th to 90th $240 to $1,445Professionalmedian $240 · 10th to 90th $155 to $324
$200$500$1Kfacility $759professional $240

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$758.58
Typical High
$1,445.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$239.88
Typical High
$288.40
BCBS
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$194.98
Typical High
$380.19
Cigna
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$1,023.29
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$151.36
Typical High
$371.54
Medcost
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$275.42
Typical High
$407.38
United
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$186.21
Typical High
$309.03

Where South Carolina sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 45th of 51

$245

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.