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TP53 Gene Test For A Known Family Change

Indiana rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$251

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $251 for this service. The price depends on where it is billed: about $251 from a physician practice, and about $309 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$251$166 to $251
FacilityA hospital or hospital-owned outpatient department$309$309 to $617

How much rates vary

Facilitymedian $309 · 10th to 90th $275 to $933Professionalmedian $251 · 10th to 90th $123 to $275
$200$500$1K$2Kfacility $309professional $251

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$478.63
Typical High
$933.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$251.19
Typical High
$275.42
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$933.25
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$245.47
Cigna
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$275.42
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$275.42
Typical High
$446.68
United
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$354.81
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$186.21
Typical High
$371.54

Where Indiana sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 41st of 51

$251

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.