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TP53 Gene Test For A Known Family Change

Alabama rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$174

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $186 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$186$132 to $355
FacilityA hospital or hospital-owned outpatient department$174$174 to $174

How much rates vary

Facilitymedian $174 · 10th to 90th $174 to $263Professionalmedian $186 · 10th to 90th $129 to $355
$200$500$1Kfacility $174professional $186

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$478.63
Aetna
Setting
Professional
Modifier
None
Typical Low
$239.88
Median
$354.81
Typical High
$354.81
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$120.23
Median
$177.83
Typical High
$177.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$47.86
Median
$70.79
Typical High
$70.79
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31 + 55 · Aftercare only + 99 · Multiple modifiers
Typical Low
$190.55
Median
$229.09
Typical High
$229.09
Cigna
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$263.03
Typical High
$977.24
Cigna
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$138.04
Typical High
$398.11
United
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$275.42
Typical High
$309.03
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$169.82
Typical High
$186.21

Where Alabama sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$174

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.