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TP53 Gene Test For A Known Family Change

California rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

Facilitymedian $724 · 10th–90th $263$1,8200%5%10%10th90th$724Professionalmedian $263 · 10th–90th $126$1,5490%10%10th90th$263$50.0$100.0$200.0$500.0$1.0K$2.0K$5.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$380.19
Median
$691.83
Typical High
$1,819.70
Aetna
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$263.03
Typical High
$2,041.74
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$794.33
Typical High
$1,548.82
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$186.21
Typical High
$602.56
Blue Shield
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$1,318.26
Typical High
$3,090.30
Blue Shield
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$426.58
Cigna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$537.03
Typical High
$1,122.02
Cigna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$213.80
Typical High
$891.25
Contra Costa Health
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$309.03
Typical High
$416.87
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$338.84
Typical High
$537.03
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$1,479.11
Median
$1,479.11
Typical High
$1,479.11
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$2,290.87
Typical High
$2,290.87
Providence
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$371.54
Typical High
$812.83
Providence
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$323.59
Typical High
$660.69
The Alliance
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$309.03
Typical High
$3,715.35
United
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$309.03
Typical High
$354.81
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$691.83