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TP53 Gene Test For A Known Family Change

Pennsylvania rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

Facilitymedian $589 · 10th–90th $263$1,1480%10%10th90th$589Professionalmedian $251 · 10th–90th $162$6760%20%10th90th$251$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$588.84
Typical High
$1,096.48
Aetna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$251.19
Typical High
$1,096.48
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$1,122.02
Median
$1,513.56
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$501.19
Typical High
$1,047.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$269.15
Typical High
$549.54
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$213.80
Typical High
$407.38
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$309.03
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$371.54
Typical High
$575.44
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$588.84
Typical High
$1,096.48
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$251.19
Typical High
$1,096.48
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$758.58
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
United
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$186.21
Typical High
$457.09