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TP53 Gene Test For A Known Family Change

Oklahoma rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$275

Typical negotiated rate. In Oklahoma, July 2026.

Insurers have agreed to pay about $275 for this service. The price depends on where it is billed: about $229 from a physician practice, and about $309 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$229$129 to $331
FacilityA hospital or hospital-owned outpatient department$309$229 to $389

How much rates vary

Facilitymedian $309 · 10th to 90th $229 to $776Professionalmedian $229 · 10th to 90th $129 to $389
$100$200$500$1K$2Kfacility $309professional $229

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$309.03
Typical High
$776.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$229.09
Typical High
$389.05
BCBS
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$295.12
Typical High
$295.12
Cigna
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$831.76
Typical High
$831.76
Cigna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$138.04
Typical High
$446.68
Medica
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$309.03
Typical High
$537.03
Medica
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$457.09
United
Setting
Facility
Modifier
Global
Typical Low
$109.65
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$204.17

Where Oklahoma sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 30th of 51

$275

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.