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TP53 Gene Test For A Known Family Change

Florida rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$224

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $224 for this service. The price depends on where it is billed: about $214 from a physician practice, and about $501 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$214$186 to $251
FacilityA hospital or hospital-owned outpatient department$501$263 to $832

How much rates vary

Facilitymedian $501 · 10th to 90th $224 to $1,660Professionalmedian $214 · 10th to 90th $162 to $309
$10$20$50$100$200$500$1Kfacility $501professional $214

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$501.19
Typical High
$1,659.59
Aetna
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$213.80
Typical High
$275.42
AvMed
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$309.03
Typical High
$363.08
AvMed
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$309.03
Typical High
$309.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$234.42
Typical High
$1,258.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$223.87
Typical High
$537.03
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$575.44
Typical High
$575.44
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$186.21
Typical High
$263.03
Molina
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$251.19
Typical High
$309.03
United
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$275.42
Typical High
$309.03
United
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$131.83
Typical High
$407.38
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$309.03

Where Florida sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 50th of 51

$224

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.