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TP53 Gene Test For A Known Family Change

Florida rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$200

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $186 from a physician practice, and about $575 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$186$148 to $251
FacilityA hospital or hospital-owned outpatient department$575$407 to $575

How much rates vary

Facilitymedian $575 · 10th to 90th $234 to $575Professionalmedian $186 · 10th to 90th $129 to $380
$10$20$50$100$200$500$1Kfacility $575professional $186

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$223.87
Typical High
$616.60
Aetna
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$199.53
Typical High
$251.19
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$93.33
Median
$100.00
Typical High
$125.89
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$37.15
Median
$39.81
Typical High
$50.12
AvMed
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$309.03
Typical High
$371.54
AvMed
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$309.03
Typical High
$309.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$239.88
Typical High
$1,258.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$204.17
Typical High
$537.03
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$575.44
Typical High
$575.44
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$186.21
Median
$186.21
Typical High
$269.15
Molina
Setting
Professional
Modifier
None
Typical Low
$186.21
Median
$186.21
Typical High
$251.19
United
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$309.03
United
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$131.83
Typical High
$407.38
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$288.40
Median
$309.03
Typical High
$309.03

Where Florida sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 48th of 51

$200

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.