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TP53 Gene Test For A Known Family Change

South Dakota rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$347

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $347 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$214 to $589
FacilityA hospital or hospital-owned outpatient department$347$347 to $589

How much rates vary

Facilitymedian $347 · 10th to 90th $288 to $589Professionalmedian $309 · 10th to 90th $158 to $741
$200$500$1Kfacility $347professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$213.80
Typical High
$346.74
Aetna
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$204.17
Typical High
$288.40
Cigna
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
Cigna
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$588.84
Typical High
$741.31
Medica
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$346.74
Typical High
$346.74
Medica
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$275.42
Typical High
$562.34
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$512.86
Median
$724.44
Typical High
$851.14
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$186.21
Typical High
$309.03
Wellmark
Setting
Professional
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$309.03

Where South Dakota sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 12th of 51

$347

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.