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TP53 Gene Test For A Known Family Change

Minnesota rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$309

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $309 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $309 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$269 to $372
FacilityA hospital or hospital-owned outpatient department$309$288 to $676

How much rates vary

Facilitymedian $309 · 10th to 90th $275 to $1,148Professionalmedian $309 · 10th to 90th $186 to $617
$200$500$1K$2Kfacility $309professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Aetna
Setting
Professional
Modifier
None
Typical Low
$288.40
Median
$288.40
Typical High
$371.54
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$177.83
Median
$309.03
Typical High
$354.81
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$275.42
Typical High
$309.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$977.24
Typical High
$2,884.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$407.38
Typical High
$602.56
Health Partners
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$954.99
Typical High
$2,238.72
Health Partners
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$549.54
Medica
Setting
Facility
Modifier
None
Typical Low
$371.54
Median
$489.78
Typical High
$616.60
Medica
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$346.74
Typical High
$1,548.82
United
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$245.47
Typical High
$724.44
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$144.54
Median
$144.54
Typical High
$144.54
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$57.54
Median
$57.54
Typical High
$57.54
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$144.54
Median
$144.54
Typical High
$186.21
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$57.54
Median
$57.54
Typical High
$74.13

Where Minnesota sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 23rd of 51

$309

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.