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TP53 Gene Test For A Known Family Change

Massachusetts rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$309

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $309 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $427 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$251 to $309
FacilityA hospital or hospital-owned outpatient department$427$309 to $708

How much rates vary

Facilitymedian $427 · 10th to 90th $229 to $912Professionalmedian $309 · 10th to 90th $186 to $692
$100.0$1.0K$10.0Kfacility $427professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$537.03
Typical High
$912.01
Aetna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$229.09
Typical High
$933.25
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$354.81
Typical High
$1,000.00
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$912.01
BCBS
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$389.05
Typical High
$616.60
BCBS
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Cigna
Setting
Facility
Modifier
Global
Typical Low
$204.17
Median
$239.88
Typical High
$489.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$371.54
Typical High
$660.69
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$162.18
Median
$1,778.28
Typical High
$7,079.46
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$446.68
Typical High
$524.81
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$501.19
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$354.81
Typical High
$1,000.00
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$912.01
United
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$616.60

Where Massachusetts sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $309 · 25th of 51
AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.