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TP53 Gene Test For A Known Family Change

Illinois rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$263

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $263 for this service. The price depends on where it is billed: about $251 from a physician practice, and about $575 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$251$186 to $398
FacilityA hospital or hospital-owned outpatient department$575$372 to $1,175

How much rates vary

Facilitymedian $575 · 10th to 90th $324 to $2,455Professionalmedian $251 · 10th to 90th $145 to $490
$100$200$500$1K$2K$5Kfacility $575professional $251

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$489.78
Typical High
$933.25
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$125.89
Median
$239.88
Typical High
$467.74
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$50.12
Median
$95.50
Typical High
$186.21
Aetna
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$251.19
Typical High
$275.42
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$125.89
Median
$125.89
Typical High
$138.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$50.12
Median
$50.12
Typical High
$54.95
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$371.54
Median
$446.68
Typical High
$3,981.07
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$239.88
Typical High
$239.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$741.31
Typical High
$1,412.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$398.11
Typical High
$478.63
Hally Health
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$446.68
Typical High
$645.65
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$398.11
Median
$398.11
Typical High
$398.11
United
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$371.54
Typical High
$389.05
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$186.21
Typical High
$309.03

Where Illinois sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 34th of 51

$263

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.