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TP53 Gene Test For A Known Family Change

Illinois rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$295

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $295 for this service. The price depends on where it is billed: about $263 from a physician practice, and about $468 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$263$251 to $372
FacilityA hospital or hospital-owned outpatient department$468$316 to $617

How much rates vary

Facilitymedian $468 · 10th to 90th $251 to $794Professionalmedian $263 · 10th to 90th $186 to $562
$200$500$1K$2Kfacility $468professional $263

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$467.74
Typical High
$630.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$263.03
Typical High
$524.81
BCBS
Setting
Facility
Modifier
Global
Typical Low
$371.54
Median
$501.19
Typical High
$3,981.07
BCBS
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$239.88
Typical High
$239.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$363.08
Median
$707.95
Typical High
$1,412.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$371.54
Typical High
$524.81
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$478.63
Typical High
$691.83
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$398.11
United
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$616.60
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$169.82
Typical High
$309.03

Where Illinois sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 28th of 51

$295

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.