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TP53 Gene Test For A Known Family Change

Colorado rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$324

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $324 for this service. The price depends on where it is billed: about $234 from a physician practice, and about $759 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$234$186 to $251
FacilityA hospital or hospital-owned outpatient department$759$407 to $1,288

How much rates vary

Facilitymedian $759 · 10th to 90th $240 to $1,549Professionalmedian $234 · 10th to 90th $129 to $331
$200$500$1K$2Kfacility $759professional $234

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$194.98
Median
$676.08
Typical High
$1,445.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$234.42
Typical High
$331.13
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$912.01
Typical High
$1,548.82
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$128.82
Typical High
$309.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$199.53
Typical High
$933.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$165.96
Typical High
$446.68
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$309.03
Typical High
$467.74
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$436.52
Typical High
$645.65
Select Health
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$575.44
Typical High
$645.65
Select Health
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$309.03
Typical High
$457.09
United
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$309.03
Typical High
$457.09
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$229.09

Where Colorado sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 13th of 51

$324

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.