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TP53 Gene Test For A Known Family Change

Connecticut rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$269

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $269 for this service. Most negotiated rates run $186 to $407.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $389 · 10th to 90th $229 to $813Professionalmedian $204 · 10th to 90th $158 to $447
$200$500$1Kfacility $389professional $204

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$204.17
Typical High
$213.80
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$380.19
Typical High
$758.58
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$186.21
Typical High
$398.11
Cigna
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$912.01
Typical High
$1,548.82
Cigna
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$354.81
Typical High
$645.65
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$407.38
Typical High
$501.19
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$186.21
Typical High
$398.11
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$83.18
Median
$102.33
Typical High
$107.15
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$33.88
Median
$40.74
Typical High
$42.66

Where Connecticut sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 30th of 51

$269

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.