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TP53 Gene Test For A Known Family Change

New York rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated October 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$263

Typical negotiated rate. In New York, October 2026.

Insurers have agreed to pay about $263 for this service. The price depends on where it is billed: about $263 from a physician practice, and about $309 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$263$195 to $398
FacilityA hospital or hospital-owned outpatient department$309$186 to $617

How much rates vary

Facilitymedian $309 · 10th to 90th $186 to $794Professionalmedian $263 · 10th to 90th $138 to $646
$20$50$100$200$500$1Kfacility $309professional $263

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$263.03
Typical High
$954.99
Aetna
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$165.96
Typical High
$263.03
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$794.33
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$446.68
Typical High
$776.25
CDPHP
Setting
Professional
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$309.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$302.00
Median
$660.69
Typical High
$794.33
Cigna
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$398.11
Typical High
$1,047.13
Emblem Health
Setting
Facility
Modifier
None
Typical Low
$263.03
Median
$389.05
Typical High
$691.83
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$186.21
Median
$263.03
Typical High
$407.38
Excellus BCBS
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$186.21
Typical High
$186.21
Excellus BCBS
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$263.03
Typical High
$354.81
MVP Health Care
Setting
Facility
Modifier
None
Typical Low
$13.80
Median
$309.03
Typical High
$616.60
MVP Health Care
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$229.09
Typical High
$630.96
United
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$309.03
Typical High
$389.05
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$151.36
Typical High
$467.74
Univera
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$186.21
Typical High
$380.19
Univera
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$263.03
Typical High
$338.84
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$83.18
Median
$83.18
Typical High
$131.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$33.88
Median
$33.88
Typical High
$52.48

Where New York sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New York· 32nd of 51

$263

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.