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TP53 Gene Test For A Known Family Change

Missouri rates for HCPCS 81353

Checks a blood or saliva sample for one particular change in the TP53 gene that has already been found in a relative. TP53 normally helps stop cells from growing out of control, and inherited changes in it raise the risk of several cancers, sometimes at a young age. Because the exact change being looked for is already known, only that one spot is examined.

Rates data updated July 2026.

How much does TP53 Gene Test For A Known Family Change cost?

$309

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $309 for this service. The price depends on where it is billed: about $269 from a physician practice, and about $398 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$269$148 to $363
FacilityA hospital or hospital-owned outpatient department$398$309 to $537

How much rates vary

Facilitymedian $398 · 10th to 90th $302 to $708Professionalmedian $269 · 10th to 90th $123 to $603
$200$500$1Kfacility $398professional $269

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$512.86
Typical High
$707.95
Aetna
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$288.40
Typical High
$630.96
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$1,071.52
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$125.89
Typical High
$549.54
BCBS
Setting
Facility
Modifier
Global
Typical Low
$426.58
Median
$457.09
Typical High
$794.33
BCBS
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$309.03
Typical High
$524.81
Cigna
Setting
Facility
Modifier
Global
Typical Low
$436.52
Median
$645.65
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$162.18
Typical High
$426.58
Medica
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$371.54
Typical High
$1,479.11
Medica
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$186.21
Typical High
$1,548.82
United
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$309.03
Typical High
$371.54
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$186.21
Typical High
$416.87

Where Missouri sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 24th of 51

$309

AK $692DE $204

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.