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CYP2D6 Drug Metabolism Gene Test

Tennessee rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated October 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$447

Typical negotiated rate. In Tennessee, October 2026.

Insurers have agreed to pay about $447 for this service. Most negotiated rates run $269 to $1,000.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $933 · 10th to 90th $302 to $1,318Professionalmedian $398 · 10th to 90th $204 to $3,388
$50$100$200$500$1K$2Kfacility $933professional $398

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$354.81
Typical High
$691.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$354.81
Typical High
$512.86
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$169.82
Median
$177.83
Typical High
$257.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$67.61
Median
$70.79
Typical High
$104.71
BCBS Tennessee
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$446.68
Typical High
$446.68
Cigna
Setting
Facility
Modifier
None
Typical Low
$302.00
Median
$933.25
Typical High
$1,412.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$245.47
Typical High
$616.60
Lucent Health
Setting
Professional
Modifier
None
Typical Low
$2,238.72
Median
$3,388.44
Typical High
$3,388.44
United
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$269.15
Typical High
$446.68

Where Tennessee sits

The same service costs 3.7 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Tennessee· 24th of 51

$447

AK $1,023FL $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.