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CYP2D6 Drug Metabolism Gene Test

Tennessee rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated July 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$380

Typical negotiated rate. In Tennessee, July 2026.

Insurers have agreed to pay about $380 for this service. The price depends on where it is billed: about $355 from a physician practice, and about $724 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$355$339 to $447
FacilityA hospital or hospital-owned outpatient department$724$407 to $1,479

How much rates vary

Facilitymedian $724 · 10th to 90th $339 to $1,950Professionalmedian $355 · 10th to 90th $234 to $537
$10.0$50.0$200.0$1.0K$5.0Kfacility $724professional $355

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$1,230.27
Typical High
$1,949.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$338.84
Median
$354.81
Typical High
$512.86
BCBS
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$446.68
Typical High
$446.68
Cigna
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$933.25
Typical High
$1,513.56
Cigna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$263.03
Typical High
$616.60
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$2,137.96
Median
$2,137.96
Typical High
$2,137.96
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$2,238.72
Median
$3,388.44
Typical High
$3,388.44
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$446.68
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$269.15
Typical High
$446.68

Where Tennessee sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Tennessee $380 · 34th of 51
AK $1,023VT $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.