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CYP2D6 Drug Metabolism Gene Test

Alabama rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated October 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$513

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $513 for this service. The price depends on where it is billed: about $269 from a physician practice, and about $589 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$269$204 to $513
FacilityA hospital or hospital-owned outpatient department$589$589 to $589

How much rates vary

Facilitymedian $589 · 10th to 90th $513 to $589Professionalmedian $269 · 10th to 90th $191 to $513
$200$500$1Kfacility $589professional $269

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$691.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$512.86
Typical High
$512.86
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$177.83
Median
$257.04
Typical High
$257.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$70.79
Median
$104.71
Typical High
$104.71
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$229.09
Median
$338.84
Typical High
$338.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$380.19
Typical High
$1,445.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$213.80
Typical High
$1,862.09
United
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$407.38
Typical High
$446.68
United
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$251.19
Typical High
$269.15

Where Alabama sits

The same service costs 3.7 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 12th of 51

$513

AK $1,023FL $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.