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CYP2D6 Drug Metabolism Gene Test

Alabama rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated July 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$447

Typical negotiated rate. In Alabama, July 2026.

Insurers have agreed to pay about $447 for this service. The price depends on where it is billed: about $355 from a physician practice, and about $550 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$355$275 to $513
FacilityA hospital or hospital-owned outpatient department$550$447 to $692

How much rates vary

Facilitymedian $550 · 10th to 90th $407 to $832Professionalmedian $355 · 10th to 90th $269 to $513
$200$500$1Kfacility $550professional $355

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$512.86
Typical High
$691.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$354.81
Typical High
$512.86
BCBS
Setting
Facility
Modifier
Global
Typical Low
$549.54
Median
$660.69
Typical High
$891.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$275.42
Typical High
$436.52
Cigna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$380.19
Typical High
$1,445.44
Cigna
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$213.80
Typical High
$1,862.09
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$407.38
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$446.68

Where Alabama sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 25th of 51

$447

AK $1,023VT $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.