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CYP2D6 Drug Metabolism Gene Test

West Virginia rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated October 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$447

Typical negotiated rate. In West Virginia, October 2026.

Insurers have agreed to pay about $447 for this service. The price depends on where it is billed: about $380 from a physician practice, and about $871 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$380$224 to $661
FacilityA hospital or hospital-owned outpatient department$871$372 to $1,122

How much rates vary

Facilitymedian $871 · 10th to 90th $372 to $1,349Professionalmedian $380 · 10th to 90th $191 to $832
$200$500$1K$2Kfacility $871professional $380

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$371.54
Median
$371.54
Typical High
$371.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$371.54
Typical High
$380.19
CareSource
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$537.03
Typical High
$741.31
Cigna
Setting
Facility
Modifier
None
Typical Low
$371.54
Median
$870.96
Typical High
$1,348.96
Cigna
Setting
Professional
Modifier
None
Typical Low
$588.84
Median
$645.65
Typical High
$2,187.76
United
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$269.15
Typical High
$269.15
United
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$223.87
Typical High
$831.76

Where West Virginia sits

The same service costs 3.7 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

West Virginia· 21st of 51

$447

AK $1,023FL $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.