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CYP2D6 Drug Metabolism Gene Test

Maine rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated October 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$407

Typical negotiated rate. In Maine, October 2026.

Insurers have agreed to pay about $407 for this service. Most negotiated rates run $269 to $562.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $603 · 10th to 90th $437 to $1,259Professionalmedian $295 · 10th to 90th $229 to $661
$200$500$1K$2Kfacility $603professional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$363.08
Typical High
$363.08
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$588.84
Typical High
$1,258.93
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$269.15
Typical High
$363.08
Cigna
Setting
Facility
Modifier
None
Typical Low
$707.95
Median
$707.95
Typical High
$1,023.29
Cigna
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$457.09
Typical High
$457.09
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$269.15
Median
$446.68
Typical High
$794.33
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$363.08
Median
$363.08
Typical High
$363.08
United
Setting
Professional
Modifier
None
Typical Low
$269.15
Median
$269.15
Typical High
$794.33

Where Maine sits

The same service costs 3.7 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 31st of 51

$407

AK $1,023FL $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.