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CYP2D6 Drug Metabolism Gene Test

Hawaii rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated October 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$537

Typical negotiated rate. In Hawaii, October 2026.

Insurers have agreed to pay about $537 for this service. Most negotiated rates run $479 to $562.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $537 · 10th to 90th $417 to $676
$500$1Kprofessional $537

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Cigna
Setting
Professional
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$537.03
HMSA
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$478.63
Typical High
$645.65
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$501.19
Median
$537.03
Typical High
$870.96
United
Setting
Professional
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$676.08
University Health Alliance
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$537.03
Typical High
$812.83

Where Hawaii sits

The same service costs 3.7 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Hawaii· 9th of 51

$537

AK $1,023FL $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.