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CYP2D6 Drug Metabolism Gene Test

Delaware rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated October 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$302

Typical negotiated rate. In Delaware, October 2026.

Insurers have agreed to pay about $302 for this service. Most negotiated rates run $204 to $372.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $372 · 10th to 90th $295 to $794Professionalmedian $269 · 10th to 90th $191 to $676
$200$500$1K$2Kfacility $372professional $269

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$371.54
Median
$371.54
Typical High
$371.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$371.54
Typical High
$371.54
Cigna
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$794.33
Cigna
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$302.00
Typical High
$2,187.76
United
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$269.15
Typical High
$676.08

Where Delaware sits

The same service costs 3.7 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Delaware· 48th of 51

$302

AK $1,023FL $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.