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CYP2D6 Drug Metabolism Gene Test

Washington, DC rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated July 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$339

Typical negotiated rate. In Washington, DC, July 2026.

Insurers have agreed to pay about $339 for this service. The price depends on where it is billed: about $339 from a physician practice, and about $339 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$339$331 to $355
FacilityA hospital or hospital-owned outpatient department$339$339 to $537

How much rates vary

Facilitymedian $339 · 10th to 90th $339 to $759Professionalmedian $339 · 10th to 90th $324 to $575
$1.0$10.0$100.0$1.0Kfacility $339professional $339

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$338.84
Typical High
$354.81
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$645.65
Typical High
$2,290.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$724.44
Median
$758.58
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$524.81
Typical High
$2,041.74
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$794.33
Typical High
$912.01
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$537.03
Typical High
$1,023.29
United
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$204.17
Typical High
$426.58

Where Washington, DC sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Washington, DC $339 · 48th of 51
AK $1,023VT $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.