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CYP2D6 Drug Metabolism Gene Test

Maryland rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated July 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$339

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $339 for this service. Most negotiated rates run $269 to $380.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $191 · 10th to 90th $191 to $1,023Professionalmedian $339 · 10th to 90th $204 to $501
$200$500$1K$2Kfacility $191professional $339

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$338.84
Typical High
$407.38
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$323.59
Typical High
$398.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$281.84
Typical High
$794.33
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$537.03
Typical High
$676.08
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$1,023.29
United
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$204.17
Typical High
$398.11
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$223.87
Median
$354.81
Typical High
$354.81

Where Maryland sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 47th of 51

$339

AK $1,023VT $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.