go back

CYP2D6 Drug Metabolism Gene Test

Connecticut rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated July 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$447

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $447 for this service. The price depends on where it is billed: about $302 from a physician practice, and about $708 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$302$245 to $589
FacilityA hospital or hospital-owned outpatient department$708$447 to $912

How much rates vary

Facilitymedian $708 · 10th to 90th $447 to $1,259Professionalmedian $302 · 10th to 90th $204 to $1,000
$200$500$1K$2Kfacility $708professional $302

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$645.65
Typical High
$1,258.93
Aetna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$302.00
Typical High
$1,000.00
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$707.95
Typical High
$1,230.27
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$245.47
Typical High
$1,071.52
Cigna
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$724.44
Typical High
$1,659.59
Cigna
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$537.03
Typical High
$912.01
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$467.74
Typical High
$851.14
United
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$371.54
Typical High
$676.08

Where Connecticut sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 18th of 51

$447

AK $1,023VT $269

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.