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CYP2D6 Drug Metabolism Gene Test

Arkansas rates for HCPCS 81226

Examines the CYP2D6 gene, which carries the instructions for a liver enzyme that breaks down a large share of common medicines. The test checks for the usual variants, including extra or missing copies of the gene, and reports whether a person clears those drugs slowly, normally, or unusually fast.

Rates data updated October 2026.

How much does CYP2D6 Drug Metabolism Gene Test cost?

$513

Typical negotiated rate. In Arkansas, October 2026.

Insurers have agreed to pay about $513 for this service. The price depends on where it is billed: about $380 from a physician practice, and about $513 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$380$269 to $562
FacilityA hospital or hospital-owned outpatient department$513$513 to $661

How much rates vary

Facilitymedian $513 · 10th to 90th $447 to $708Professionalmedian $380 · 10th to 90th $234 to $562
$200$500facility $513professional $380

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$562.34
Typical High
$691.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$562.34
Typical High
$562.34
BCBS Arkansas
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$512.86
Typical High
$707.95
BCBS Arkansas
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$562.34
Typical High
$562.34
CareSource
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$446.68
Cigna
Setting
Facility
Modifier
None
Typical Low
$354.81
Median
$575.44
Typical High
$831.76
Cigna
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$234.42
Typical High
$676.08
United
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$407.38
Typical High
$446.68
United
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$269.15
Typical High
$457.09
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$177.83
Median
$281.84
Typical High
$281.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$70.79
Median
$114.82
Typical High
$114.82

Where Arkansas sits

The same service costs 3.7 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arkansas· 11th of 51

$513

AK $1,023FL $275

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.