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CYP2C19 Drug Metabolism Gene Test

West Virginia rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated October 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$295

Typical negotiated rate. In West Virginia, October 2026.

Insurers have agreed to pay about $295 for this service. The price depends on where it is billed: about $245 from a physician practice, and about $562 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$245$145 to $427
FacilityA hospital or hospital-owned outpatient department$562$282 to $871

How much rates vary

Facilitymedian $562 · 10th to 90th $240 to $871Professionalmedian $245 · 10th to 90th $123 to $537
$100$200$500$1Kfacility $562professional $245

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$239.88
Typical High
$245.47
CareSource
Setting
Professional
Modifier
None
Typical Low
$288.40
Median
$346.74
Typical High
$478.63
Cigna
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$562.34
Typical High
$870.96
Cigna
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$416.87
Typical High
$1,412.54
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$1,096.48
Median
$1,096.48
Typical High
$1,096.48
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$144.54
Typical High
$537.03

Where West Virginia sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

West Virginia· 20th of 51

$295

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.