go back

CYP2C19 Drug Metabolism Gene Test

Michigan rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated July 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$275

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $275 for this service. The price depends on where it is billed: about $240 from a physician practice, and about $275 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$240$219 to $275
FacilityA hospital or hospital-owned outpatient department$275$275 to $347

How much rates vary

Facilitymedian $275 · 10th to 90th $263 to $513Professionalmedian $240 · 10th to 90th $158 to $347
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $275professional $240

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$512.86
Aetna
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$275.42
Typical High
$346.74
BCBS
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$331.13
Typical High
$562.34
BCBS
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$218.78
Typical High
$218.78
CareSource
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
CareSource
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$323.59
Typical High
$389.05
Cigna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$165.96
Typical High
$407.38
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$295.12
Typical High
$676.08
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$288.40
Typical High
$389.05
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$338.84
Typical High
$660.69
United
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$288.40
Typical High
$346.74
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$173.78
Typical High
$295.12

Where Michigan sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Michigan $275 · 28th of 51
AK $661VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.