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CYP2C19 Drug Metabolism Gene Test

Georgia rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated October 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$331

Typical negotiated rate. In Georgia, October 2026.

Insurers have agreed to pay about $331 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $339 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$141 to $427
FacilityA hospital or hospital-owned outpatient department$339$288 to $479

How much rates vary

Facilitymedian $339 · 10th to 90th $219 to $1,000Professionalmedian $324 · 10th to 90th $74 to $617
$50$100$200$500$1Kfacility $339professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$512.86
Aetna
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$213.80
Typical High
$281.84
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$331.13
Typical High
$1,000.00
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$363.08
Typical High
$575.44
CareSource
Setting
Professional
Modifier
None
Typical Low
$346.74
Median
$380.19
Typical High
$389.05
Cigna
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$562.34
Typical High
$891.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$446.68
Typical High
$1,148.15
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$288.40
Median
$398.11
Typical High
$549.54
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$288.40
Median
$354.81
Typical High
$512.86
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$173.78
Typical High
$616.60
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$97.72
Median
$114.82
Typical High
$141.25
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$38.90
Median
$45.71
Typical High
$56.23

Where Georgia sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Georgia· 10th of 51

$331

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.