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CYP2C19 Drug Metabolism Gene Test

Oregon rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated July 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$309

Typical negotiated rate. In Oregon, July 2026.

Insurers have agreed to pay about $309 for this service. The price depends on where it is billed: about $288 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$288$263 to $427
FacilityA hospital or hospital-owned outpatient department$324$288 to $550

How much rates vary

Facilitymedian $324 · 10th to 90th $288 to $708Professionalmedian $288 · 10th to 90th $174 to $562
$100.0$200.0$500.0$1.0Kfacility $324professional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$380.19
Median
$549.54
Typical High
$1,318.26
Aetna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$281.84
Typical High
$812.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$758.58
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$323.59
Typical High
$457.09
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$630.96
Typical High
$758.58
Moda Health
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$288.40
Typical High
$407.38
Moda Health
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$354.81
Typical High
$416.87
Pacific Source
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$588.84
Pacific Source
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$549.54
Providence
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$407.38
Typical High
$851.14
Providence
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$323.59
Typical High
$416.87
Regence BlueShield
Setting
Facility
Modifier
Global
Typical Low
$436.52
Median
$870.96
Typical High
$1,148.15
Regence BlueShield
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$245.47
Typical High
$346.74
United
Setting
Facility
Modifier
Global
Typical Low
$436.52
Median
$436.52
Typical High
$436.52
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$346.74

Where Oregon sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Oregon $309 · 13th of 51
AK $661VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.