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CYP2C19 Drug Metabolism Gene Test

Alaska rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated July 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$661

Typical negotiated rate. In Alaska, July 2026.

Insurers have agreed to pay about $661 for this service. The price depends on where it is billed: about $661 from a physician practice, and about $1,023 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$661$288 to $977
FacilityA hospital or hospital-owned outpatient department$1,023$646 to $1,380

How much rates vary

Facilitymedian $1,023 · 10th to 90th $288 to $2,089Professionalmedian $661 · 10th to 90th $204 to $977
$200.0$500.0$1.0K$2.0Kfacility $1,023professional $661

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$2,041.74
Typical High
$3,388.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$870.96
Typical High
$1,905.46
Cigna
Setting
Facility
Modifier
Global
Typical Low
$812.83
Median
$812.83
Typical High
$812.83
Moda Health
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$1,318.26
Moda Health
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$288.40
Typical High
$933.25
Premera BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,023.29
Median
$1,122.02
Typical High
$1,380.38
Premera BCBS
Setting
Professional
Modifier
Global
Typical Low
$436.52
Median
$660.69
Typical High
$660.69
Providence
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$812.83
Typical High
$1,380.38
Providence
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$263.03
Typical High
$263.03
United
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$776.25
Typical High
$776.25
United
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$295.12
Typical High
$870.96

Where Alaska sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Alaska $661 · 1st of 51
AK $661VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.