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CYP2C19 Drug Metabolism Gene Test

Washington, DC rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated October 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$219

Typical negotiated rate. In Washington, DC, October 2026.

Insurers have agreed to pay about $219 for this service. Most negotiated rates run $209 to $234.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $490 · 10th to 90th $219 to $1,122Professionalmedian $219 · 10th to 90th $123 to $363
$200$500$1K$2Kfacility $490professional $219

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$218.78
Median
$218.78
Typical High
$218.78
Aetna
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$218.78
Typical High
$218.78
CareFirst
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$208.93
Typical High
$234.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$489.78
Typical High
$1,122.02
Cigna
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$371.54
Typical High
$2,137.96
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$588.84
Typical High
$616.60
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$173.78
Typical High
$346.74

Where Washington, DC sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Washington, DC· 43rd of 51

$219

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.