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CYP2C19 Drug Metabolism Gene Test

Florida rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated October 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$178

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $178 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $537 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$132 to $234
FacilityA hospital or hospital-owned outpatient department$537$372 to $537

How much rates vary

Facilitymedian $537 · 10th to 90th $234 to $537Professionalmedian $174 · 10th to 90th $102 to $339
$10$20$50$100$200$500$1Kfacility $537professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$177.83
Typical High
$588.84
Aetna
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$177.83
Typical High
$234.42
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$67.61
Median
$87.10
Typical High
$117.49
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.92
Median
$35.48
Typical High
$46.77
Ambetter
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$177.83
Typical High
$177.83
AvMed
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$288.40
Typical High
$354.81
AvMed
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$288.40
Typical High
$288.40
Cigna
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$281.84
Typical High
$1,174.90
Cigna
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$204.17
Typical High
$524.81
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$537.03
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$173.78
Typical High
$173.78
Molina
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$363.08
United
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
United
Setting
Professional
Modifier
None
Typical Low
$102.33
Median
$125.89
Typical High
$398.11
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$288.40
Typical High
$288.40

Where Florida sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 50th of 51

$178

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.