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CYP2C19 Drug Metabolism Gene Test

Alabama rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated October 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$174

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$129 to $339
FacilityA hospital or hospital-owned outpatient department$174$174 to $174

How much rates vary

Facilitymedian $174 · 10th to 90th $174 to $245Professionalmedian $174 · 10th to 90th $123 to $339
$100$200$500$1Kfacility $174professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$446.68
Aetna
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$338.84
Typical High
$338.84
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$114.82
Median
$165.96
Typical High
$165.96
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$45.71
Median
$67.61
Typical High
$67.61
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$147.91
Median
$218.78
Typical High
$218.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$234.42
Median
$245.47
Typical High
$933.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$109.65
Median
$138.04
Typical High
$1,230.27
United
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$263.03
Typical High
$288.40
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$162.18
Typical High
$173.78

Where Alabama sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 51st of 51

$174

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.