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CYP2C19 Drug Metabolism Gene Test

Alabama rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated July 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$234

Typical negotiated rate. In Alabama, July 2026.

Insurers have agreed to pay about $234 for this service. The price depends on where it is billed: about $229 from a physician practice, and about $263 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$229$178 to $339
FacilityA hospital or hospital-owned outpatient department$263$191 to $339

How much rates vary

Facilitymedian $263 · 10th to 90th $166 to $437Professionalmedian $229 · 10th to 90th $174 to $339
$100.0$200.0$500.0$1.0K$2.0Kfacility $263professional $229

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$338.84
Typical High
$446.68
Aetna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$229.09
Typical High
$338.84
BCBS
Setting
Facility
Modifier
Global
Typical Low
$162.18
Median
$194.98
Typical High
$263.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$177.83
Typical High
$281.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$245.47
Typical High
$933.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$138.04
Typical High
$1,230.27
United
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$263.03
Typical High
$288.40
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$295.12

Where Alabama sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Alabama $234 · 43rd of 51
AK $661VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.