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CYP2C19 Drug Metabolism Gene Test

Oklahoma rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated July 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$363

Typical negotiated rate. In Oklahoma, July 2026.

Insurers have agreed to pay about $363 for this service. The price depends on where it is billed: about $219 from a physician practice, and about $479 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$219$174 to $288
FacilityA hospital or hospital-owned outpatient department$479$288 to $646

How much rates vary

Facilitymedian $479 · 10th to 90th $219 to $759Professionalmedian $219 · 10th to 90th $123 to $363
$10.0$100.0$1.0K$10.0Kfacility $479professional $219

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$288.40
Typical High
$741.31
Aetna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$218.78
Typical High
$363.08
BCBS
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$537.03
Typical High
$758.58
BCBS
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$275.42
Cigna
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$776.25
Typical High
$794.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$151.36
Typical High
$426.58
Medica
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$363.08
Typical High
$489.78
Medica
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$436.52
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$288.40
Typical High
$346.74
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$190.55

Where Oklahoma sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Oklahoma $363 · 7th of 51
AK $661VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.