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CYP2C19 Drug Metabolism Gene Test

Oklahoma rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated October 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$275

Typical negotiated rate. In Oklahoma, October 2026.

Insurers have agreed to pay about $275 for this service. The price depends on where it is billed: about $151 from a physician practice, and about $457 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$151$123 to $295
FacilityA hospital or hospital-owned outpatient department$457$288 to $646

How much rates vary

Facilitymedian $457 · 10th to 90th $219 to $776Professionalmedian $151 · 10th to 90th $123 to $1,445
$200$500$1Kfacility $457professional $151

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$239.88
Typical High
$269.15
Aetna
Setting
Professional
Modifier
None
Typical Low
$6.03
Median
$213.80
Typical High
$309.03
BCBS Oklahoma
Setting
Facility
Modifier
None
Typical Low
$389.05
Median
$537.03
Typical High
$758.58
BCBS Oklahoma
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$275.42
Typical High
$316.23
Cigna
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$794.33
Typical High
$794.33
Cigna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$213.80
Medica
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$380.19
Typical High
$501.19
Medica
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$288.40
Typical High
$1,445.44
United
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$288.40
Typical High
$346.74
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$190.55

Where Oklahoma sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 28th of 51

$275

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.