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CYP2C19 Drug Metabolism Gene Test

Utah rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated October 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$229

Typical negotiated rate. In Utah, October 2026.

Insurers have agreed to pay about $229 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $316 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$135 to $288
FacilityA hospital or hospital-owned outpatient department$316$135 to $347

How much rates vary

Facilitymedian $316 · 10th to 90th $135 to $1,000Professionalmedian $174 · 10th to 90th $123 to $407
$100$200$500$1Kfacility $316professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$67.61
Median
$213.80
Typical High
$281.84
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$26.92
Median
$87.10
Typical High
$112.20
Aetna
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
Cigna
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$316.23
Typical High
$831.76
Cigna
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$302.00
Typical High
$537.03
Molina
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$371.54
Typical High
$416.87
Regence BlueShield
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$338.84
Typical High
$1,174.90
Regence BlueShield
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$245.47
Typical High
$331.13
Select Health
Setting
Facility
Modifier
None
Typical Low
$204.17
Median
$204.17
Typical High
$204.17
U of Utah Health Plan
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$426.58
Typical High
$588.84
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$173.78
Typical High
$173.78

Where Utah sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Utah· 41st of 51

$229

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.