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CYP2C19 Drug Metabolism Gene Test

Connecticut rates for HCPCS 81225

A blood or cheek-swab test that examines common variations in the CYP2C19 gene, which controls one of the liver enzymes that break medicines down. The result predicts whether a person clears certain drugs quickly, normally, or slowly, so a prescriber can pick a suitable medicine or adjust the dose. Clopidogrel, several antidepressants, and some acid-reducing medicines depend on this enzyme.

Rates data updated July 2026.

How much does CYP2C19 Drug Metabolism Gene Test cost?

$288

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $288 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $457 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$162 to $380
FacilityA hospital or hospital-owned outpatient department$457$288 to $589

How much rates vary

Facilitymedian $457 · 10th to 90th $263 to $813Professionalmedian $195 · 10th to 90th $135 to $646
$100.0$200.0$500.0$1.0Kfacility $457professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$416.87
Typical High
$812.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$194.98
Typical High
$645.65
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$457.09
Typical High
$794.33
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$173.78
Typical High
$691.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$467.74
Typical High
$1,071.52
Cigna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$346.74
Typical High
$602.56
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$302.00
Typical High
$467.74
United
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
United
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$245.47
Typical High
$501.19

Where Connecticut sits

The same service costs 3.8 times more in Alaska than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Connecticut $288 · 19th of 51
AK $661VT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.